STAND UP - Sedentary Behaviour in Older Adults: Investigating a New Therapeutic Paradigm (STAND-UP)

University of Leicester

Status: Completed

Conditions: Older Adults

Treatments: Behavioral: Standing; Behavioral: Walking; Behavioral: Sitting

Study type: Interventional

Funder types: Other

Identifiers

NCT02453204

MR/K025090/1 (Other Grant/Funding Number)

UOLE0482 (Other Identifier)

CRN18120 (Registry Identifier)

0482

Details and patient eligibility

About

Research has shown that reducing the time spent sitting can reduce the risk of many diseases, such as diabetes and heart disease, and improve health. It is estimated that many older adults typically spend 70% of their waking day sitting, but little is known about whether reducing sitting promotes health and well-being in this age group. The aim of this research is to investigate the health effects of reducing sitting time by replacing it with short periods of standing or walking in adults over the age of 65.

Enrollment: 76 patients

Sex: All

Ages: 65 to 79 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults aged between 65 to 79 years inclusive
• Able to walk (without any assistive devices and not requiring assistance from another person)
• Ability to communicate in and understand English to participate in the informed consent process.

Exclusion criteria

• Regular purposeful exercise (≥75 minutes of self-reported vigorous exercise per week)
• Inability to stand or undertake light ambulation
• Psychological condition which limits participation in the study (e.g. dementia)
• Inability to communicate or understand English
• Steroid use
• Use of glucose lowering medication
• Inability to give informed consent

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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76 participants in 3 patient groups

Sitting

Experimental group

Description:

Participants will remain sitting throughout the test period whilst undertaking typical sedentary behaviours such as watching TV, using a computer, reading and writing. Walking and standing will be restricted.

Treatment:

Behavioral: Sitting

Standing

Experimental group

Description:

Participants will be asked to break their sitting time by standing for five minutes every 30 minutes. Participants will be asked to stand in the same position with no further instructions provided. In total, individuals will accumulate 12 bouts (60 minutes) of standing throughout the test period.

Treatment:

Behavioral: Standing

Walking

Experimental group

Description:

The walking condition will be identical to standing, but the breaks in sitting time will be punctuated with five minute bouts of self-paced walking rather than standing.

Treatment:

Behavioral: Walking