Standard Versus Fanning Techniques for Endoscopic Ultrasound-Fine Needle Aspiration (EUS-FNA)

Shyam Varadarajulu

Status: Completed

Conditions: Pancreatic Tumors

Treatments: Procedure: Standard; Procedure: Fanning

Study type: Interventional

Funder types: Other

Identifiers

NCT01501903

F110907002

Details and patient eligibility

About

Endoscopic Ultrasound (EUS)-guided biopsy is the most ideal technique for evaluating a growth in the pancreas. EUS-guided biopsies yield a definitive diagnosis in greater than 80% of cases. In 15-20% of the cases, a definitive diagnosis cannot be made despite multiple attempts. One of the reasons why a diagnosis cannot be made is due to the focal location of the cancer; i.e., the cancer can be situated in a corner of a big mass and the needle fails to sample the cancer cells. The fanning technique is a method where the needle moves in multiple directions within a mass and therefore there is a better chance of the cancer cells being sampled compared to the standard technique where the needle moves in only one direction. The diagnostic performance of both these techniques has not been compared in a randomized fashion.

Full description

Fanning technique: Fine Needle Aspiration (FNA) performed in multiple directions within a mass.

Standard technique: FNA performed in unidirectional fashion.

Enrollment: 52 patients

Sex: All

Ages: 19 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age > 19 years
• Solid Pancreatic Mass Lesions

Exclusion criteria

• Age < 19 years
• Coagulopathy
• Unable to consent

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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52 participants in 2 patient groups

Standard

Active Comparator group

Description:

Biopsy using standard technique of FNA

Treatment:

Procedure: Standard

Fanning

Other group

Description:

Biopsy using fanning technique

Treatment:

Procedure: Fanning