Standardization of Anti-Seizure Medications Withdrawals After Seizure Remission in Young Patients With Epilepsy (ADORE)

Asan Medical Center

Status: Enrolling

Conditions: Epilepsy; Epilepsy in Children

Study type: Observational

Funder types: Other

Identifiers

NCT05740423

HC20C0164 (Other Grant/Funding Number)

Details and patient eligibility

About

The proper period of anti-seizure medication (ASM) treamtment is important for decreasing side effect of ASM and recurrence of seizure. We evaluate reliable risk factor analysis for safe withdrawal of ASM in children with epilepsy. Futhermore, we develop the scoring system for prediction of seizure recurrence to set the standard for safe withdrawal of ASM.

Full description

The proper period of anti-seizure medication (ASM) treamtment is important for decreasing side effect of ASM and recurrence of seizure. We evaluate reliable risk factor analysis for safe withdrawal of ASM in children with epilepsy. Futhermore, we develop the scoring system for prediction of seizure recurrence to set the standard for safe withdrawal of ASM.

The enroll criteria as follow:

1. patients with epilepsy or acute provoked seizure accroding to the ILAE definition
2. patients who have been 2 years of seizure free with or without ASM

The patients with seizure recurrence during follow-up or end of follow-up period of 24 months will end this stutdy.

Enrollment: 1,200 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with Epilepsy or acute provoked seizure according to the ILAE guideline
• Patients with 2 years of seizure free periods

Exclusion criteria

• Uncertain diagnosis of epilepsy or acute provoked seizure
• Patients who do not want to participate in the study