Staphylococcus Lugdunensis Prosthetic Joint Infection

Civil Hospices of Lyon

Status: Completed

Conditions: Prosthetic Joint Infection; Staphylococcal Infections

Treatments: Other: Prothestic joint infection due to Staphylococcus lugdunensis

Study type: Observational

Funder types: Other

Identifiers

NCT04409392

20-202

Details and patient eligibility

About

Staphylococcus lugdunensis is a coagulase-negative staphylococcus belonging to the human commensal cutaneous flora, and has been little studied in the field of prosthetic joint infections. However, it shares many virulence traits with Staphylococcus aureus, including many adhesins and its ability to form biofilm, and the few series of cases reports a significant failure rate.

Enrollment: 84 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• infection of joint prosthesis (whatever its type) with Staphylococcus lugdunensis defined by the positivity of at least 2 gold-standard samples (joint puncture, intraoperative samples) with S. lugdunensis; OR
• a single positive gold-standard sample or positive blood cultures AND formal clinical, radiological, biological and / or pathological arguments in favor of an infection of joint prosthesis AND absence of other pathogenic agent

Exclusion criteria

• none

Trial design

84 participants in 1 patient group

Prothestic joint infection due to Staphylococcus lugdunensis

Description:

Patients having had a prosthetic joint infection with Staphylococcus lugdunensis

Treatment:

Other: Prothestic joint infection due to Staphylococcus lugdunensis