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Staphylokinase and ABO Group Phenotype: New Players in Staphylococcus Aureus Implant-associated Infections Development

N

Nantes University Hospital (NUH)

Status

Completed

Conditions

Staphylococcal Infection

Treatments

Other: IAI infection
Other: Staphylococcus aureus nasal carriage infection

Study type

Observational

Funder types

Other

Identifiers

NCT02812446
RC15_0456

Details and patient eligibility

About

The purpose of this study is to identify bacterial and/or clinical features involved in the pathogenesis of Staphylococcus aureus implant-associated infections (IAI). Materials & methods: In total, 57 IAI S. aureus and 31 nasal carriage (NC) S. aureus isolates were studied. Staphylococcus aureus genetic background was obtained by microarray analysis. Multilocus sequence typing was performed to determine clonal complexes (CC). Biofilm production was investigated by resazurin and crystal violet methods

Enrollment

88 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • infected patients with S. Aureus IAI infection
  • noninfected patients screened for S. aureus nasal colonization at the orthopedic consultation ward

Exclusion criteria

  • minor

Trial design

88 participants in 2 patient groups

IAI patients group
Description:
patients with Staphylococcus aureus of implant-associated infections
Treatment:
Other: IAI infection
control group
Description:
patients with Staphylococcus aureus nasal carriage
Treatment:
Other: Staphylococcus aureus nasal carriage infection

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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