Start Treatment and Recovery for Opioid Use Disorder (STAR)

University of Vermont

Status: Completed

Conditions: Mental Disorder; Opioid-use Disorder; Opioid Medication Assisted Treatment

Treatments: Other: Bridge Clinic

Study type: Interventional

Funder types: Other; Other U.S. Federal agency; NIH

Identifiers

NCT04505540

CHRMS: 18-0695

1R21DA049859-01 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is 1) to evaluate whether emergency department-initiated medically assisted treatment with Buprenorphine/Naloxone in patients presenting with opioid use disorder will produce positive outcomes at 1 week, 3 months and 6 months after treatment initiation.

Full description

The emergency department is a critical missed opportunity to engage patients with opioid use disorder in medication-assisted treatment, the most effective current treatment for the disorder. Patients presenting at the emergency department with opioid use disorder will be given the opportunity to immediately start medication assisted treatment with Naloxone/Buprenorphine then referred either to a specialized addiction bridge clinic or a local waivered provider for further treatment.

Enrollment: 104 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient at Emergency Department
• Diagnosis opioid use disorder according to criteria Diagnostic and Statistical Manual (DSM) 5

Exclusion criteria

• Participating in alternate treatment program for opioid use disorder
• Prisoner
• Inability to communicate
• Psychosis
• Suicidality
• History of Buprenorphine injection
• Critical Illness

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

104 participants in 1 patient group

Bridge Clinic

Experimental group

Description:

Medication assisted treatment supervised by addiction bridge clinic until stabilized in treatment.

Treatment:

Other: Bridge Clinic