Statins and ARBs on Rheumatoid Activity

Sherief Abd-Elsalam

Status and phase: Enrolling; Phase 3

Conditions: Rheumatoid Arthritis

Treatments: Drug: Angiotensin receptor blockers; Drug: Statins

Study type: Interventional

Funder types: Other

Identifiers

NCT03770702

Rheumatoid

Details and patient eligibility

About

Investigational and comparative study between the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients

Full description

The study aims at ivestigating and comparing the anti-inflammatory effectof both angiotensin reeptor blockers and statins on rheumatoid arthritis disease activity on Egyptian patients

Enrollment: 45 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Rheumatoid arthritis.

Exclusion criteria

• Pregnant or lactating
• Hepatic or renal impairment.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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45 participants in 3 patient groups

Control group

No Intervention group

Description:

No intervention

Angiotensin receptor blockers

Active Comparator group

Description:

ARB ( Angiotensin receptor blockers) + Traditional therpy.

Treatment:

Drug: Angiotensin receptor blockers

Statins

Active Comparator group

Description:

Statin + Traditional therapy.

Treatment:

Drug: Statins