Stellate Ganglion Block as Novel Treatment for Heart Failure Patients

Mina sobhi said fam

Status and phase: Enrolling; Phase 3; Phase 2

Conditions: Stellate Ganglion Block

Treatments: Procedure: Stellate Ganglion Block

Study type: Interventional

Funder types: Other

Identifiers

NCT06244056

Stellate Ganglion Block 2023

Details and patient eligibility

About

Stellate Ganglion Block as Novel Treatment for Heart Failure Patients

Full description

Stellate Ganglion Block as Novel Treatment for Heart Failure Patients

Enrollment: 108 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18 : 70 years old.
• NYHA Class III-IV Heart Failure.
• Heart failure with a reduced ejection fraction (HFrEF) LVEF ≤ 40% calculated using 2D echocardiography and Biplane Simpson's .
• Optimal tolerated Medical Therapy for Heart Failure.

Exclusion criteria

• Active Malignancy.
• Acute heart failure including pulmonary edema or cardiogenic shock.
• Severe, life-threatening non-cardiac disease.
• Pregnancy.
• Localized infection.
• Coagulopathy or anticoagulated patients.
• Refused this procedure.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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108 participants in 3 patient groups

Narrow QRS complex Heart failure patients

No Intervention group

Description:

Narrow QRS complex Heart failure patients with optimal medical treatment.

: Narrow QRS complex Heart failure patients

Active Comparator group

Description:

: Narrow QRS complex Heart failure patients with optimal medical treatment with stellate ganglion block.

Treatment:

Procedure: Stellate Ganglion Block

Wide QRS complex heart failure patients

Active Comparator group

Description:

Wide QRS complex heart failure patients with optimal medical treatment who were non responders to CRT( retrospective and prospective) with stellate ganglion block.

Treatment:

Procedure: Stellate Ganglion Block