Stellate Ganglion Block in Obstructive Sleep Apnea

Zeng Changhao

Status: Enrolling

Conditions: Obstructive Sleep Apnea

Treatments: Device: Stellate ganglion block; Drug: Lidocaine Hydrochloride Injection; Behavioral: routine rehabilitation treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT06249490

SGB-OSA

Details and patient eligibility

About

The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are:

• Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were randomly divided into two groups, all provided with routine therapy. Based on this, the experimental group was given stellate ganglion block. The video fluoroscopic swallowing study was done to test the swallowing function before and after the study.

Full description

Obstructive Sleep Apnea is of increasingly high prevalence.

The goal of this clinical trial is to test the efficacy of stellate ganglion block in Obstructive Sleep Apnea. The main question it aims to answer are:

• Can stellate ganglion block improve Obstructive Sleep Apnea? Patients were randomly divided into two groups, all provided with routine therapy. Based on this, the experimental group was given stellate ganglion block. The video fluoroscopic swallowing study was done to test the swallowing function before and after the study.

Enrollment: 80 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged over 18 years diagnosed with Obstructive Sleep Apnea by polysomnography
• Patients with moderate to severe Obstructive Sleep Apnea
• Patients who have undergone continuous positive airway pressure treatment for at least 3 months but have not achieved satisfactory therapeutic effects
• Patients who voluntarily agree to receive stellate ganglion block treatment and sign the informed consent form

Exclusion criteria

• Patients with a history of allergy or contraindications to local anesthetics or corticosteroids
• Patients with severe cardiovascular, cerebrovascular, respiratory, hepatic, or renal diseases
• Patients with a history of neck surgery or cervical spine disease
• Patients with psychiatric disorders or other medical conditions that may affect the safety or effectiveness of Stellate Ganglion Block treatment
• Pregnant or lactating women
• Patients who have participated in other clinical trials within the past 3 months

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups

The experimental group

Experimental group

Description:

All participants were given routine rehabilitation treatment by professional rehabilitation therapists, including exercise therapy, guided education, psychological therapy, acupuncture and massage therapy.The experimental group was given Stellate Ganglion Block.

Treatment:

Drug: Lidocaine Hydrochloride Injection

Behavioral: routine rehabilitation treatment

Device: Stellate ganglion block

The control group

Active Comparator group

Description:

All participants were given routine rehabilitation treatment by professional rehabilitation therapists, including exercise therapy, guided education, psychological therapy, acupuncture and massage therapy.

Treatment:

Behavioral: routine rehabilitation treatment