Stem Cell Therapy in Traumatic Brain Injury

Neurogen Brain and Spine Institute

Status and phase: Withdrawn; Phase 1

Conditions: Traumatic Brain Injury

Treatments: Biological: Autologous bone marrow mononuclear cell transplantation

Study type: Interventional

Funder types: Other

Identifiers

NCT02028104

NGBSI-06

Details and patient eligibility

About

The purpose of this study was to study the effect of stem cell therapy on common symptoms in patients with Traumatic Brain Injury

Sex: All

Ages: 6 months to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed cases of chronic traumatic brain injury
• Age above 6 months

Exclusion criteria

• presence of acute infections such as Human immunodeficiency virus/Hepatitis B - Virus/Hepatitis C Virus
• malignancies
• bleeding tendencies
• pneumonia
• renal failure
• severe liver dysfunction
• severe anemia [Hemoglobin < 8]
• any bone marrow disorder
• space occupying lesion in brain
• other acute medical conditions such as respiratory infection and pyrexia
• pregnancy
• lactation

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

stem cells

Experimental group

Description:

autologous bone marrow mononuclear cell transplantation

Treatment:

Biological: Autologous bone marrow mononuclear cell transplantation