Steps Against the Burden of Parkinson's Disease - StepuP

Tel Aviv Sourasky Medical Center

Status: Not yet enrolling

Conditions: Parkinson Disease

Treatments: Device: VR

Study type: Interventional

Funder types: Other

Identifiers

NCT06538909

0569-23-TLV

Details and patient eligibility

About

The goals of our StepuP project are:

1. To understand the kinematic and neural mechanisms underlying walking improvements due to treadmill training with and without VR-enabled gait adaptations in people with PD;
2. To assess to what extent improvements in walking due to treadmill training, as measured in the laboratory, transfer to improvements in daily life mobility;
3. To understand the mechanisms underlying the transfer from improvements in walking to improvements in mobility in daily life in people with PD;
4. To understand for whom treadmill training improves walking characteristics in the laboratory and for whom it does not, and to understand for whom treadmill training improves mobility in daily life and for whom it does not.

Enrollment: 21 estimated patients

Sex: All

Ages: 25 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Specific criteria for Parkinson's disease - PD

• Diagnosis of Parkinson's disease according to the MDS World Movement Disorders Society criteria Disease severity H&Y I-III
• Score section 3.10 (ability to walk) MDS-UPDRS 3.10 ≥ 1
• MoCA cognitive assessment > 15
• Stable cardiovascular condition, ability to perform aerobic activity at low to moderate intensity
• Without orthopedic diseases and other diseases that affect the quality of walking, at the decision of the researcher.

Exclusion criteria

• Moderate or severe depression (BDI-II ≥18)
• Orthopedic diseases and other diseases that affect the quality of walking, at the decision of the researcher

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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21 participants in 1 patient group

PD with VR int.

Experimental group

Description:

Parkinson's disease patients using Virtual reality intervention that include physical activity and cognitive

Treatment:

Device: VR