Sterify Gel as an Adjunct to Non-Surgical Periodontal Therapy in Periodontitis

San Donato Group (GSD)

Status: Not yet enrolling

Conditions: Periodontitis

Study type: Observational

Funder types: Other

Identifiers

NCT07672665

Sterify

Details and patient eligibility

About

This retrospective observational study will evaluate the clinical response to Sterify Gel, a sterile mucoadhesive polymeric hydrogel, when used as an adjunct to non-surgical periodontal therapy in adult patients with stage II, III, or IV periodontitis.

The study will analyze already existing anonymized clinical records from patients treated at the Periodontal Unit of IRCCS Ospedale San Raffaele in Milan, Italy. Patients included in the analysis received scaling and root planing/minimally invasive non-surgical periodontal therapy, followed by local application of Sterify Gel into periodontal pockets with probing depth greater than 4 mm.

The main objective is to assess reduction in periodontal pocket depth from baseline to 6, 12, and 24 weeks. Other periodontal clinical parameters, including clinical attachment level, gingival recession, bleeding, plaque score, tooth mobility, and furcation involvement, will also be evaluated.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients aged >18 years
• Diagnosis of stage II, III, or IV periodontitis
• Non-smokers
• Negative medical history
• Patients treated with scaling and root planing/minimally invasive non-surgical periodontal therapy plus mucoadhesive polymeric hydrogel
• Patients enrolled in supportive periodontal care

Exclusion criteria

• Smokers
• Pregnancy
• Surgical re-treatment during the maintenance period