Steroid Before Thyroidectomy

University of Bern

Status: Completed

Conditions: Thyroid Surgery for Benign Disease

Treatments: Drug: Placebo; Drug: Dexamethason Helvepharm ®

Study type: Interventional

Funder types: Other

Identifiers

NCT00619086

KEK_49_05

Details and patient eligibility

About

We evaluated the effects of giving a single dose of steroid before thyroid surgery in a single institutional, double-blinded, randomized controlled trial. Postoperative nausea, pain, and vocal function were significantly improved after steroid administration compared to controls.

Enrollment: 72 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing thyroid surgery for benign disease

Exclusion criteria

• Depression
• Chronic pain disorder
• Insulin dependent diabetes mellitus
• History of PONV
• Pregnancy
• Age < 18 years
• Received antiemetic therapy within 48 hours

Trial design

72 participants in 2 patient groups, including a placebo group

A, 1

Placebo Comparator group

Description:

Placebo 45 minutes prior to surgery

Treatment:

Drug: Placebo

A, 2

Active Comparator group

Description:

8 mg Dexamethasone 45 minutes prior to surgery

Treatment:

Drug: Dexamethason Helvepharm ®