Steroid Injection for Sickle Cell Arthropathy Pain Therapy

Salem Anaesthesia Pain Clinic

Status: Completed

Conditions: Sickle Cell Abnormality; Sickle Cell Disease

Treatments: Drug: Dexamethasone 20mg

Study type: Observational

Funder types: Other

Identifiers

NCT05983055

SalemAn2018 SCD arthro injectn

Details and patient eligibility

About

Sickle cell disease (SCD) is associated with arthropathy. Arthropathy may require periarticular corticosteroid injection therapy. This observational study examines efficacy, and safety of steroid injections in SCD patients. Data collection includes patient's gender, age, race, smoking history, alcohol intake, analgesic use, pain score, sleep quality, limb joint injections, post-injection analgesia, and post-injection complication. Pain is measured using numeric pain scale. Sleep quality is measured using Likert scale.

Full description

Sickle cell disease (SCD) is associated with arthropathy. Arthropathy causes pain which may require periarticular corticosteroid injection therapy. There is inadequate data about the suitability of steroid therapy in SCD patients. This prospective observational study examines the efficacy, and safety of periarticular steroid injections in SCD patients.

This is a cohort study of adult patients undergoing pain management at a pain clinic in Canada. Data collection includes patient's gender, age, race, smoking history, alcohol intake, analgesic usage, numeric pain score, sleep quality score, limb joint injections, post-injection analgesia, and post-injection complication. Pain is measured using numeric pain rating scale. Sleep quality is measured using the Likert Sleep scale. A change in the pain or sleep scores by 2-points is considered significant. Data are analyzed with IBM® SPSS® Statistics 25; using Student's t-test, ANOVA, Pearson Chi-square test, and regression analysis. P-value <0.05 is considered significant.

Enrollment: 50 patients

Sex: All

Ages: 20 to 99 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• adult chronic pain patients
• sickle cell disease arthropathy
• periarticular steroid injection therapy
• regular sleep diary
• regular pain diary
• informed consent for therapy and diary review

Exclusion criteria

• pediatric patients
• patient without sickle cell disease arthropathy
• patient without periarticular steroid injection
• irregular sleep diary
• irregular pain diary