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Steroids Added to Dithranol and Narrow Band UVB(Ultraviolet B) (UVBnb) in Psoriasis (DIPSO)

University of Zurich (UZH) logo

University of Zurich (UZH)

Status and phase

Withdrawn
Phase 4

Conditions

Psoriasis

Treatments

Drug: Steroid active treatment

Study type

Interventional

Funder types

Other

Identifiers

NCT01429870
KEK-ZH 2010-0171-5 (Other Identifier)
DIPSO

Details and patient eligibility

About

Objective(s):

(i) To assess the effect of adjunctive topical steroids in the combined treatment with UVBnb and dithranol on the remission time after therapy till a relapse of psoriasis defined as 50% loss of PASI (Psoriasis Area and Severity Index) improvement obtained through the antecedent treatment.

(ii) To assess the impact of adjuvant topical steroids in the combined treatment with UVBnb and dithranol on the clearing time of psoriasis lesions under therapy (PASI 75).

  • Trial with medicinal product

Full description

(i) To assess the effect of adjunctive topical steroids in the combined treatment with UVBnb and dithranol on the remission time after therapy till a relapse of psoriasis defined as 50% loss of PASI (Psoriasis Area and Severity Index) improvement obtained through the antecedent treatment.

(ii) To assess the impact of adjuvant topical steroids in the combined treatment with UVBnb and dithranol on the clearing time of psoriasis lesions under therapy (PASI 75).

  • Trial with medicinal product

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Moderate to severe psoriasis of the chronic-plaque and / or guttata type

Exclusion criteria

  • Participation in a Goeckerman therapy regimen within 6 months previous to the present study

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Quadruple Blind

0 participants in 2 patient groups, including a placebo group

Steroid active treatment
Active Comparator group
Description:
Triamcinolone acetonide 0.1% in unguentum leniens topically
Treatment:
Drug: Steroid active treatment
Vehicle
Placebo Comparator group
Description:
unguentum leniens topically
Treatment:
Drug: Steroid active treatment

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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