Stiffness Measurement of Liver Tumors and Visceral Parenchyma

China Medical University

Status: Unknown

Conditions: Hepatocellular Carcinoma

Treatments: Other: stiffness measurement using ARFI

Study type: Observational

Funder types: Other

Identifiers

NCT01343212

DMR100-IRB-055

Details and patient eligibility

About

The investigators are measuring hepatocellular carcinoma(HCC)stiffness using Acoustic Radiation Force Impulse (ARFI) technique to enhance the diagnostic accuracy for HCC stratifications and treatment efficacy.

Full description

Regression modelings as well as validity testings including cut-off identification will be acquired by performing both qualitative and quantitative measurements of HCC using reference diagnostic modalities e.g. pathology grading, dynamic CT scanning, etc.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

with HCC

Exclusion criteria

• subjects with liver cancer other than HCC
• subjects with treated HCC
• post major abdominal surgery
• contraindications to liver tumor biopsy
• contraindications to local percutaneous treatment of liver tumors
• ARFI measurement low quality

Trial design

50 participants in 1 patient group

newly diagnosed HCC

Description:

* Subjects with newly diagnosed untreated hepatocellular carcinoma (HCC) will be enrolled. * Subjects with the following conditions will be excluded: liver cancer other than HCC, treated HCC, post major abdominal surgery, contraindications to liver tumor biopsy, contraindications to local percutaneous treatment of liver tumors, low quality ARFI measurement

Treatment:

Other: stiffness measurement using ARFI