STN-Stimulation Versus Best Medical Treatment in Advanced PD

German Parkinson Study Group (GPS)

Status and phase

Completed

Phase 3

Conditions

Parkinson's Disease

Treatments

Procedure: Implantation of stimulation electrodes in the STN

Study type

Interventional

Funder types

Other

Identifiers

NCT00196911

Grant 01 GI 0201/01 GI 0401

A 125/00

Details and patient eligibility

About

Assessment of the therapeutic effect of deep brain stimulation of the subthalamic nucleus compared with drug treatment alone in patients with advanced Parkinson's disease.

Full description

Patients are randomized either to medical treatment or subthalamic stimulation. The observation period was 6 months. The primary outcome criterium: PDQ-39 and UPDRS III.

Sex

All

Ages

20 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

advanced Parkinson's disease with UPDRS III score >29/104 or Dyskinesia score > 2 or tremor >2

Exclusion criteria

age>75 years depression psychosis surgical contraindications