StO2 Performance Measured on Admission to the Emergency Department in the Assessment of Drug Poisoning (IMACS)

Toulouse University Hospital

Status: Completed

Conditions: Drug Poisoning

Treatments: Device: Measurement of StO2

Study type: Interventional

Funder types: Other

Identifiers

NCT01861262

12 506 03

Details and patient eligibility

About

The primary purpose of the protocol is to evaluate the StO2 performance measured at the admission to the emergency department to identify hemodynamic failure at the admission or within the first three hours of monitoring patients with drug poisoning.

The study hypotheses are:

• The early detection of hypoperfusion by StO2, essential to prevent the development of collapse.
• To limit hemodynamic failure effects, reduce morbidity and mortality of drug poisoning, hospital stay and cost.

Full description

The procedure is a measurement and non-invasive monitoring system of percentage of oxygen saturation of haemoglobin in tissues using infrared technology. The system used in the study is the tissue oxygenation monitor InSpectraTM StO2 Spot Check, Model 300 consisting of a clamp applied to the base of the thumb of the patient.

Enrollment: 300 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• admitted to the emergency department,
• whose pattern of hospitalization is drug poisoning, defined on data from the patient's interrogation or his family if the patient is not able to answer,
• Written informed consent signed by the patient or, if he's unable to sign, by a companion,
• Affiliated to medical insurance

Exclusion criteria

• Patients without thenar eminence or having a disease of the thenar,
• Refusal to participate in the study,
• Participation in another biomedical research,
• Patient under guardianship, trusteeship or judicial protection,
• Pregnant women or nursing mothers

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

300 participants in 1 patient group

Measurement of StO2

Experimental group

Description:

The procedure is a measurement and non-invasive monitoring system of percentage of oxygen saturation of haemoglobin in tissues using infrared technology. The system used in the study is the tissue oxygenation monitor InSpectraTM StO2 Spot Check, Model 300 consisting of a clamp applied to the base of the thumb of the patient.

Treatment:

Device: Measurement of StO2