Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy

Services Hospital, Lahore

Status: Completed

Conditions: Renal Stone

Treatments: Procedure: Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.; Procedure: Extracorporeal shock wave lithotripsy

Study type: Interventional

Funder types: Other

Identifiers

NCT05725122

S23

Details and patient eligibility

About

Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%. Tamsulosin is an alpha-blocker widely used in urological practice to relax smooth muscle of the prostate and bladder neck. Its role as part of medical expulsion therapy for the treatment of patients with kidney and ureteric stones has proved to be of considerable success. However, its role in clearing upper ureteric stones as an adjunct to ESWL is controversial. Therefore, this study will be conducted to evaluate its role in stone clearance along with extracorporeal shock wave lithotripsy in patients with upper ureteric stones

Enrollment: 82 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• single upper ureteric stone
• size ranging from 6-15 mm
• stones history less than 6 months

Exclusion criteria

• Patients with urinary tract infection
• multiple ureteric stones,
• presence of a ureteric stricture distal to the stone,
• previous unsuccessful ESWL,
• concomitant use of calcium channel blockers or alpha-adrenergic antagonists
• patients with abnormal coagulation profile

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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82 participants in 2 patient groups

ESWL alone

Active Comparator group

Description:

Extracorporeal shock wave lithotripsy will be given to the patient

Treatment:

Procedure: Extracorporeal shock wave lithotripsy

ESWL combined with tamsulosin therapy

Active Comparator group

Description:

Extracorporeal shock wave lithotripsy combined with tamsulosin therapy will be given to the patient

Treatment:

Procedure: Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.