Stopping and Preventing Epileptic Seizures Using a Partial Rebreathing Mask (EpiCapno)

University of Aarhus

Status: Completed

Conditions: Epilepsy

Treatments: Device: CDA Mask; Device: Dummy mask

Study type: Interventional

Funder types: Other

Identifiers

NCT01657084

2012051485

Details and patient eligibility

About

By enabling a partial rebreathing of expired gas, a moderate respiratory acidosis is induced, without causing hypoxia in the patient.

Based on the scientific literature on the subject, the study hypothesis is that the fall in body pH will be able to stop and/or prevent epileptic brain activity.

Enrollment: 10 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Epilepsy
• 18-80 years

Exclusion criteria

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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10 participants in 3 patient groups

Tonic-clonic seizures

Experimental group

Description:

Patients with tonic-clonis seizures are observed in a video/EEG room. In the case of seizures, the treatment mask or dummy mask are administered, according to a randomized cross-over study design.

Treatment:

Device: CDA Mask

Device: Dummy mask

Generalized Paroxysms

Experimental group

Description:

Patients with generalized epileptic paroxysms are observed by EEG during baseline, treatment mask and dummy mask use, according to a randomized cross-over study design.

Treatment:

Device: CDA Mask

Device: Dummy mask

Group 3

Experimental group

Description:

Patients with epileptic paroxysms are observed by EEG during baseline, treatment mask and dummy mask use, according to a randomized cross-over study design.

Treatment:

Device: CDA Mask

Device: Dummy mask