Strain-Encoded Magnetic Resonance Imaging in Acute Myocardial Infarction (137-2005)

RWTH Aachen University

Status: Completed

Conditions: Acute Myocardial Infarction

Treatments: Procedure: cardiac MRI

Study type: Observational

Funder types: Other

Identifiers

NCT00752713

SENC in AMI

Details and patient eligibility

About

The aim of the study was therefore to evaluate whether myocardial deformation imaging performed by SENC allows for quantification of regional left ventricular function and is related to transmurality states of infarcted tissue in patients with acute myocardial infarction (AMI).

Full description

CMR was performed in 38 consecutive patients with AMI 3±1 days after successful reperfusion using a clinical 1.5 Tesla MR-scanner. Ten healthy volunteers served as controls. SENC is a technique that directly measures peak circumferential strain from long-axis views and peak longitudinal strain from short axis views. Measurements were obtained for each segment in a modified 17 segment model. Wall motion and infarcted tissue were evaluated semi-quantitatively from SSFP cine sequences and contrast-enhanced-MR-images and were then related to myocardial strain. Comparison of peak circumferential strain assessed by SENC and MR-tagging was performed.

Enrollment: 48 patients

Sex: All

Ages: 30 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with AMI after successful reperfusion
• Healthy volunteers in control group

Exclusion criteria

• No reperfusion

Trial design

48 participants in 2 patient groups

1

Description:

Patients presenting to hospital with AMI

Treatment:

Procedure: cardiac MRI

2

Description:

healthy volunteers as control group

Treatment:

Procedure: cardiac MRI