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Strain X Cardiopulmonary Test

D

Daniella Cunha Brandao

Status

Unknown

Conditions

Heart Failure

Study type

Observational

Funder types

Other

Identifiers

NCT02869178
Rafael_cardio

Details and patient eligibility

About

Introduction : Patients with heart failure (HF ) with systolic dysfunction of moderate to severe exhibit significant reduction in the ability to exercise compared to those with mild dysfunction , and have worse prognosis. However, some clinical markers of severity and diagnosis widely used in this population such as ejection fraction (EF) , are not always able to translate the actual degree of cardiac damage as well as their relationship with the cardiorespiratory fitness of these individuals and prognosis .

Objective: To evaluate the ability of the global longitudinal strain ( GLS ) in predicting exercise tolerance in heart failure patients with moderate and significant systolic dysfunction.

Enrollment

26 estimated patients

Sex

All

Ages

21 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • moderate and significant systolic dysfunction (LVEF < 45%) assessed by transthoracic echocardiography recent ( last month before evaluation ) Teichholz method , or when in the presence of contractile deficit target , by the Simpson method.

Exclusion criteria

  • deformity in the face to prevent the coupling of the mask to perform the CPET ,
  • orthopedic and neurological diseases that could make it impossible to perform the tests ,
  • patients with psychiatric disorders that restricted them to respond to the questionnaire ,
  • HF FC IV or hospitalization in the last three months ,
  • angina unstable;
  • myocardial infarction or heart surgery up to three months before the survey ;
  • FEV1 / FVC <70 % predicted characterizing obstructive respiratory disorder .

Trial contacts and locations

1

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Central trial contact

Daniella C Brandão, pHD

Data sourced from clinicaltrials.gov

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