Strategies to Improve Iodine Status in Early Pregnancy

Queen's University Belfast

Status: Completed

Conditions: Pregnancy Related; Iodine Deficiency

Treatments: Dietary Supplement: Cows' milk; Other: British Dietetic Association Iodine Fact Sheet.

Study type: Interventional

Funder types: Other

Identifiers

NCT05170997

B20/32

EAT/5578/19 (Other Grant/Funding Number)

Details and patient eligibility

About

This study aims to investigate the benefit of increased intake of cows' milk during pregnancy on iodine status.

Full description

Women of child bearing age, and those who are currently pregnant, have been found to be iodine deficient in the United Kingdom (UK). Dairy products are an essential source of iodine in the UK as iodised salt is not widely available. This study will ask women in the intervention group to drink approximately one pint of milk a day for 12 weeks during pregnancy.

Enrollment: 119 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• women at 6-16 weeks pregnant
• women receiving antenatal care within Belfast Health and Social Care Trust

Exclusion criteria

• women with known thyroid disease currently taking thyroid medication
• women with type one diabetes
• women under 18 years of age
• those unable to provide informed consent
• women with abnormal thyroid function tests at booking appointment.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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119 participants in 4 patient groups

Iodine Control

Active Comparator group

Description:

Participants taking an iodine-containing multivitamin or supplement and randomly allocated not to receive milk supply.

Treatment:

Other: British Dietetic Association Iodine Fact Sheet.

No Iodine Control

Active Comparator group

Description:

Participants not taking an iodine-containing multivitamin or supplement and randomly allocated not to receive milk supply.

Treatment:

Other: British Dietetic Association Iodine Fact Sheet.

Iodine Intervention

Experimental group

Description:

Participants taking an iodine-containing multivitamin or supplement and randomly allocated to receive milk supply.

Treatment:

Dietary Supplement: Cows' milk

Other: British Dietetic Association Iodine Fact Sheet.

No Iodine Intervention

Experimental group

Description:

Participants not taking an iodine-containing multivitamin or supplement and randomly allocated to receive milk supply.

Treatment:

Dietary Supplement: Cows' milk

Other: British Dietetic Association Iodine Fact Sheet.