Strawberries, Cognition, and Vascular Health
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About
The primary objective of this study is to investigate the effects of strawberries on cognitive responses, motor control function, and vascular and cardiometabolic risk markers in healthy older adults.
Full description
To achieve the objectives, 40 healthy men and women ≥65 years of age will consume 26 g of freeze-dried strawberries in the form of a drink-mix daily for 8 wk. Using a randomized crossover study design, the effects will be compared to the effects of 8 wk intake of a placebo drink-mix (with a 4 wk wash-out period between trials). Cognitive function measurements will be performed at baseline and 8 wk. Additionally, at each timepoint, flow-mediated vasodilation and blood pressure will be measured followed by collection of fasting blood samples to assess glucose, insulin, blood lipids (free fatty acids, triacylglycerol, total cholesterol, LDL cholesterol, and HDL cholesterol), inflammatory markers (interleukins 6 and 18), and markers of oxidative stress (oxidized LDL-C and malondialdehyde).
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Healthy men and women 65 years and older
Exclusion criteria
- stroke or myocardial infarction
- neurological disorders:
- epilepsy,
- multiple sclerosis,
- Parkinson's disease,
- stroke
- known metabolic disorders:
- liver,
- renal
- clinically diagnosed diabetes
- drug treatment for lipid reduction or hypertension,
- psychiatric medication use
Trial design
Primary purpose
Allocation
Interventional model
Masking
40 participants in 2 patient groups, including a placebo group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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