Strength-Endurance Circuit Training in Parkinson's Disease

General University Hospital, Prague

Status: Enrolling

Conditions: Parkinson Disease, Idiopathic

Treatments: Other: Endurance Training; Other: Strength-Endurance Training

Study type: Interventional

Funder types: Other

Identifiers

NCT06893055

56125

Details and patient eligibility

About

The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training.

• Does combined strength-endurance circuit training provide added benefits to physical performance, disease severity, blood biomarkers, and quality of life in PD patients compared to standalone aerobic training?

Participants will:

• undergo outcome measurements before and after the 12-week intervention and a 3-month follow-up measurement,
• visit the clinic twice a week for 1-hour training sessions.
• selected patients will be given a smartwatch with a pedometer that will count their average number of steps before, during and after the training period

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age ≥18 years
• diagnosis of idiopathic Parkinson´s disease
• Hoehn-Yahr Scale ≤ 2,5
• stable dopaminergic medication

Exclusion criteria

• age ≥75 years
• Hoehn-Yahr Scale ≥ 2,5
• deep brain stimulation
• presence of freezing
• Camptocormia
• inability to walk without support
• inability to perform study procedures
• limiting co-morbidities
• attendance at training sessions below 70%

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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90 participants in 3 patient groups

Combined Strength-Endurance Circuit Training

Experimental group

Treatment:

Other: Strength-Endurance Training

Endurance Circuit Training

Active Comparator group

Treatment:

Other: Endurance Training

Control Group

No Intervention group