Strength Training and ADLs in Childhood Leukemia and Lymphoma Patients

Technical University of Munich

Status: Completed

Conditions: Childhood Cancer

Treatments: Other: Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03934060

DJCLS 15 R/2016

Details and patient eligibility

About

Reduced activity levels and reduced muscular strength could severely impair the activities of daily living (ADLs) in pediatric leukemia and Non-Hodgkin lymphoma patients. Increased muscle strength is associated with improved accomplishment of ADLs and consequently greatest possible normality, autonomy and mobility. Primary outcome of this RCT (n=20/20) is the analysis of effects of a treatment-associated and close to every day life strength training (2-3 times/week) compared to a general exercise program (standard care).

Enrollment: 40 patients

Sex: All

Ages: 4 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with Acute Leukemia or Non-Hodgkin Lymphoma
• Diagnosed and/or treated at the Kinderklinik München Schwabing, Technische Universität München
• Informed consent as documented by signature

Exclusion criteria

• Medical contraindications regarding strength training (e.g. risk of bleeding, ...)
• Contraindications to one of the inclusion criteria mentioned above
• Inability to follow the procedures and understand the intervention and assessments of this study, e.g. due to cognitive impairment, language problems, psychological disorders etc.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Intervention

Experimental group

Description:

Supervised exercise training including specific strength training tools and general exercise contents (standard care), 2-3 times per week, 30 minutes per session

Treatment:

Other: Exercise

Control

No Intervention group

Description:

Supervised exercise training regarding general exercise contents (standard care), 2-3 times per week, 30 min per session