Strengthening Inspiratory and Oropharyngeal Muscles in Moderate Obstructive Sleep Apnea Hypopnea Syndrome (REMI SAHOS)

Centre Hospitalier Universitaire de Saint Etienne

Status

Enrolling

Conditions

Obstructive Sleep Apnea

Treatments

Other: Inspiratory and Oropharyngeal Muscle Strengthening

Study type

Interventional

Funder types

Other

Identifiers

NCT06471751

2024-A00601-46 (Other Identifier)

23GI019

Details and patient eligibility

About

The Obstructive Sleep Apnea hypopnea Syndrome (OSAS), whose prevalence is 4% of the French population, can lead to serious health consequences (risk of road accidents, onset of cardiovascular disease, etc.). OSAS corresponds to a certain number of interruptions (apneas) or reductions (hypopneas) of ventilation during sleep. The weakening of the tone of the inspiratory and oropharyngeal muscles is one of the main causes of upper airways obstruction during the inspiratory phase.

Full description

For patients with moderate OSAS, with few or no symptoms, without associated cardiovascular comorbidities, there is no recommended treatment. Rehabilitate the inspiratory and oropharyngeal muscles through muscle strengthening seems to be an alternative to this problem. Therefore, this study proposes a complete rehabilitation care evaluating the effectiveness of the strengthening of inspiratory and oropharyngeal muscles in subject with moderate OSAS.

Enrollment

38 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Moderate SAHOS (15 ≤ AHI ≤30);
Body Mass Index (BMI) < 35 ;
Patient affiliated or entitled to a social security scheme;
Patient having signed a consent to participate in the study.

Exclusion criteria

Excessive daytime sleepiness: Epworth sleepiness score > 10 ;
Professional driving and history of accidents related to sleepiness;
Severe obstructive or restrictive ventilatory disorders of neuromuscular origin authenticated by respiratory function tests;
Patients undergoing treatment for OSAS or requiring immediate initiation of continuous positive airway pressure (CPAP) or a mandibular advancement orthosis;
Patients who have stopped CPAP or orthosis treatment in less than one month;
Patients undergoing cardiorespiratory exercise rehabilitation or starting regular physical training;
Uncompensated heart failure, thoracic sternotomy surgery < 4 months;
Marked osteoporosis with history of rib fractures;
History of spontaneous pneumothorax;
Severe asthma;