Strengthening Skills Behavioral Intervention for Adults With Autism Spectrum Disorder

Southwest Autism Research & Resource Center

Status: Completed

Conditions: Autism Spectrum Disorder

Treatments: Behavioral: Strengthening Skills Program; Behavioral: PEERS Social Skills Program

Study type: Interventional

Funder types: Other

Identifiers

NCT04802434

00011585

W81XWH-20-1-0171 (Other Grant/Funding Number)

Details and patient eligibility

About

The purpose of this study is to examine changes in adaptive functioning, quality of life, and prospective memory among adults with ASD (Autism Spectrum Disorder) who complete Strengthening Skills, a multi-faceted, behavioral intervention that combines the PEERS Social Skills program with cognitive compensation training, mindfulness-based emotional regulation, and support group components. Participants and their study partners (e.g., spouse, parent, friend) will be randomly assigned to one of three groups: Strengthening Skills, PEERS only, or a delayed treatment control group. The Strengthening Skills group will meet weekly for 3 hours for 16 weeks and will learn strategies for gaining and maintaining independence and emotion regulation. Participants will also learn strategies from the PEERS Social Skills Program. The PEERS only group will meet weekly for 1.5 hours for 16 weeks and will only learn strategies from the PEERS Social Skills Program. The delayed treatment control group will participant in data collection at four time points over a 10-month wait period, after which, they will be enrolled into the Strengthening Skills Program. Behavioral self-report data will be collected and a prospective memory assessment will be conducted before and after participation in the 16-week programs. Behavioral self-report data will also be collected at remote 3- and 6-month follow-up visits.

Enrollment: 42 patients

Sex: All

Ages: 21 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Meets criteria for autism or autism spectrum on a gold-standard diagnostic assessment (Autism Diagnostic Observation Schedule-2)
• Must have a study partner (e.g., parent, spouse, sibling, friend) willing and able to complete questionnaires at all four time points
• Must be willing to be randomized to a treatment or delayed treatment control group
• Must be able to attend at least 14 of the 16 weekly intervention sessions
• English speaking: Participants must be English-speaking because the screening and behavioral measures are in English (including the intelligence estimate), as well as the intervention content

Exclusion criteria

• Non-verbal participants will be excluded to ensure test compliance and increase sample homogeneity.
• Participants with IQ (intelligence quotient) scores lower than 70 will be excluded because the interventions were developed for individuals without intellectual disability.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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42 participants in 3 patient groups

Strengthening Skills Program

Experimental group

Description:

Adults with ASD and their study partners (i.e., spouse, parent, other family member, or friend) will attend weekly 3 hour meetings for 16 weeks, during which, behavioral intervention strategies will be used to teach cognitive compensation and mindfulness-based emotion regulation skills. Strategies from the PEERS Social Skills Program will also be taught. Participants will be assigned homework assignments each week to practice skills they are learning in a real-world setting.

Treatment:

Behavioral: Strengthening Skills Program

Behavioral: PEERS Social Skills Program

PEERS Social Skills Program

Active Comparator group

Description:

Adults with ASD and their study partners (i.e., spouse, parent, other family member or friend) will attend weekly 1.5 hour meetings for 16 weeks, during which, behavioral intervention strategies will be used to teach skills for improving social relationships and handling social rejection. Participants will be assigned homework assignments each week to practice skills they are learning in a real-world setting.

Treatment:

Behavioral: PEERS Social Skills Program

Delayed Treatment Control Group

No Intervention group

Description:

Participants in the delayed treatment control group will participate in a 10-month wait period, during which they will complete data collection procedures at three time points (Baseline, Post, and 6-month follow-up).