Stress Echo and Electric Impedance Tomography (EIT) Pilot Study

RWTH Aachen University

Status: Completed

Conditions: Stress Echocardiography; Ventilation; Cardiac Output; Perfusion; Electric Impedance Tomography

Treatments: Device: EIT (Electrical Impedance Tomography)

Study type: Interventional

Funder types: Other

Identifiers

NCT01168557

Stress Echo - EIT

Details and patient eligibility

About

Electric Impedance Tomography (EIT) is a technique based on the injection of small currents and voltage measurements using electrodes on the skin surface generating cross-sectional images representing impedance change in a slice of the thorax.It is a radiation free, non- invasive and portable lung imaging technique. Impedance changes in lung ventilation as well as in lung perfusion can be shown. To investigate lung perfusion by EIT measurements, cardiac output measured by routinely undergone stress echocardiography at rest and stress are compared to parameters measured by EIT.

Full description

In 15 patients who routinely have to undergo stress echocardiography Electric Impedance Tomography (EIT) measurements are performed parallel to measurements of cardiac output at rest, low stress generated by a dosage of 10µg dobutamine, at peak generated by a dosage between 20-40µg dobutamine (individually)and at relaxation(pulse <100). Therefore prior to the examination a rubber belt with 16 integrated electrocardiographic electrodes is placed around the thorax at the fifth or sixth intercostal space, connected with an EIT device. EIT data are generated by application of a small alternating electrical current of 5mA and 50kHz and are stored and analyzed offline on a personal computer. Changes due to ventilation as well as changes due to perfusion will be measured by EIT. Cardiac output will be retrospectively compared to parameters of the EIT. EIT data are stored in a database and pseudonymized evaluated in relationship to routinely measured stress echocardiography data.

Enrollment: 8 patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• male patients >18 years who routinely have to undergo stress echocardiography
• ejection fraction >50%
• able to give informed consent

Exclusion criteria

• restrictive lung diseases
• active implants and heart pace makers and implanted converter defibrillator
• foreign metallic objects in the thorax
• Not adequate quality of imaging of stress echocardiography

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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8 participants in 1 patient group

Stress-Echo and EIT

Experimental group

Description:

Patients who routinely undergo stress-echocardiography will additionally be measured by EIT using a rubber belt, which will be placed around their chest

Treatment:

Device: EIT (Electrical Impedance Tomography)