Stress Echocardiography in the Detection of Pulmonary Arterial Hypertension in Systemic Sclerosis Patients

Paul Farand

Status: Withdrawn

Conditions: Hypertension, Pulmonary; Scleroderma, Systemic

Study type: Observational

Funder types: Other

Identifiers

NCT01202045

Projet # 10-111

Details and patient eligibility

About

The purpose of this study is to assess the value in terms of sensitivity, specificity and likelihood ratio of the stress echocardiography in the screening of pulmonary arterial hypertension in patients with systemic sclerosis and indirect signs of pulmonary arterial hypertension.

Full description

Pulmonary artery catheterization (rest and exertion) and treadmill stress echocardiography will be done to all patients of the study.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• At least one of the prespecified indirect sign of pulmonary arterial hypertension
• Able to exercise on treadmill

Exclusion criteria

• left ventricular dysfunction at rest
• Absence of pulmonary regurgitant flow
• Pregnancy or breastfeeding
• Smoking with > 60 pack-year

Trial design

0 participants in 1 patient group

systemic sclerosis patients

Description:

Every patient will have a rest echocardiography, a stress echocardiography, a right heart catheterization, a blood specimen, and a pulmonary function test.