Stress in Couples Undergoing Assisted Reproduction Technology With Donor Sperm and Its Impact on Pregnancy Outcomes

Women's Hospital School Of Medicine Zhejiang University

Status: Unknown

Conditions: Infertility, Male

Treatments: Other: Exposure: donor sperm

Study type: Observational

Funder types: Other

Identifiers

NCT04924309

20210328

Details and patient eligibility

About

Donor sperm provides a viable option for patients with significant male factor infertility. However, since the source of sperm is not from the male partner, the psychological burden of these couples is more pronounced and complex than other patients.The purpose of this study is to investigate the stress faced by participants undergoing assisted reproduction with donor sperm and to further investigate its impact on pregnancy outcomes.

Full description

The number of infertility patients has increased significantly in recent years, and infertility caused by the male partner accounts for about 30%-50% of infertility factors. Donor sperm provides a viable option for patients with significant male factor infertility. However, since the source of sperm is not from the male partner, the psychological burden of these couples is more pronounced and complex than other patients. Many factors such as social, marital, and family problems may contribute to their depressed emotional state. And the impact of these negative emotions on pregnancy outcomes cannot be ignored. In this study, investigators intend to investigate the stress faced by participants undergoing assisted reproduction with donor sperm to provide a reliable basis for future psychological interventions and health education for this group of patients and improve the quality of life of infertility patients.

Enrollment: 200 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female partners' >18< 40 years
• Male partners' >18< 40 years
• Patients undergoing assisted reproductive technology with donor sperm or husband's semen due to male factor

Exclusion criteria

• Female partners with polycystic ovary
• Female partners with insufficiency or premature ovarian failure
• Female partners with endometriosis
• Female partners with abnormal profile of thyroid hormones
• Chromosomal abnormalities of either spouse
• Mental disorder of either spouse

Trial design

200 participants in 2 patient groups

Patients undergoing assisted reproductive technology with donor sperm

Treatment:

Other: Exposure: donor sperm

Patients undergoing assisted reproductive technology with husband's semen due to male factor