Stress-Reducing Interventions in HIV+ Patients: Pilot (PEACH)

Kent State University

Status: Unknown

Conditions: Stress Disorders, Post-Traumatic; HIV Infections

Treatments: Behavioral: Prolonged Exposure Therapy

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00599599

R34MH071201-01A1

NIMH, 1 R34 MH071201-01A1

Details and patient eligibility

About

The primary aim of this project is to examine the efficacy of prolonged exposure (PE) therapy at reducing HIV-related PTSD symptoms, increasing adherence to antiretroviral medication regimens, and increasing health-related quality of life (QOL) in HIV+ patients.

Full description

HIV+ patients will be randomized to receive either PE therapy (up to 18 possible sessions) or weekly symptom monitoring (described below) and will complete measures of PTSD, adherence, and QOL pre- and post-intervention and at 3- and 6-month follow-up assessments. Secondary analyses will examine the impact of the intervention on disorders commonly comorbid with PTSD (i.e., anxiety, mood, and substance abuse/dependence disorders).

Enrollment: 70 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Must be HIV+
• Must meet PTSD diagnostic criteria
• Must be taking HIV medications
• Must be able to read and write in English

Exclusion criteria

• Current or previous diagnosis of schizophrenia, any current diagnosis with psychotic features, or current suicidal ideation
• Being in a current abusive relationship or ongoing intimate relationship with one's assailant
• Mental retardation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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70 participants in 2 patient groups

1

Experimental group

Description:

Prolonged Exposure Therapy.

Treatment:

Behavioral: Prolonged Exposure Therapy

2

No Intervention group

Description:

Weekly monitoring/Waitlist Control Group.