Stress Reduction and Anxiety: Effects on the Function and Structure of the Brain

Mass General Brigham

Status: Completed

Conditions: Generalized Anxiety Disorder

Treatments: Behavioral: Stress Reduction Intervention; Behavioral: Active Control intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT01128309

236975 (Other Grant/Funding Number)

2010P000947

Details and patient eligibility

About

The aim of the study is to test whether Generalized Anxiety Disorder (GAD) patients that participate in a Stress Reduction Intervention show a brain activation pattern (assessed by MRI) indicative of improved emotion regulation compared to an active control intervention.

Enrollment: 29 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• participation in the study 'Stress Reduction Techniques and Anxiety: Therapeutic and Neuroendocrine Effects" by Dr. Elizabeth Hoge

Exclusion criteria

• metallic implants
• left handed
• epileptic seizures
• head trauma
• weight over 350 pounds
• claustrophobia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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29 participants in 2 patient groups

Stress Reduction Intervention

Experimental group

Description:

Stress Reduction Intervention

Treatment:

Behavioral: Stress Reduction Intervention

Active Control Condition

Active Comparator group

Treatment:

Behavioral: Active Control intervention