Strict Glucose Control of Pediatric Intensive Care Unit (ICU) Patients

Children's Hospital of Philadelphia (CHOP)

Status: Withdrawn

Conditions: Cardiovascular Failure; Respiratory Failure; Trauma; Sepsis

Treatments: Procedure: Strict Glucose Control

Study type: Interventional

Funder types: Other

Identifiers

NCT00247468

2003-2-3160

Details and patient eligibility

About

The study objective is to improve morbidity and mortality of high-risk critically ill children. Our hypothesis is that a strict ICU glucose control protocol will decrease morbidity and mortality associated with hyperglycemia in a population of high-risk critically ill pediatric patients.

Sex: All

Ages: 1 month to 21 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Vasoactive infusion (e.g. dopamine, epinephrine, norepinephrine) and/or
• Invasive mechanical ventilation
• Age between 1 mo and 21 yrs

Exclusion criteria

• Type I diabetes mellitus
• Have an illness that requires insulin daily
• Recipients of solid organ transplants
• Participation in an experimental trial that might affect outcome
• Post-operative patients with planned extubation upon recovery
• Patients on a dopamine infusion of less than 3 mcg/kg/minute

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)