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Stromal Gene Expression During Pulmonary Sarcoidosis

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The Ohio State University

Status

Terminated

Conditions

Sarcoidosis

Study type

Observational

Funder types

Other

Identifiers

NCT00837668
2005H0018

Details and patient eligibility

About

to determine the genetic pathways operating at the tissue level to cause granulomatous inflammation in the lungs and lymph nodes of patients with sarcoidosis. By so doing, we hope to identify unique genetic mechanisms which will aid in the diagnosis of sarcoidosis and will help us understand the pathogenesis of this poorly understood disease.

Full description

to collect small sample of lung tissue recovered from a clinical procedure such as bronchoscopy, or a mediastinoscopy (a procedure in which a lighted instrument (mediastinoscope) is inserted through a neck incision to visually examine the structures in the top of the chest cavity and to take a sample (biopsy) of tissue.

Enrollment

110 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • diagnosis of sarcoidosis

Exclusion criteria

  • inability to provide consent

Trial design

110 participants in 1 patient group

sarcoidosis
Description:
sarcoidosis patients undergoing clinical bronchoscopy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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