Structural and Functional Changes in Neuronal Intranuclear Inclusion Disease(NIID)

Zhejiang University

Status: Unknown

Conditions: Neuronal Intranuclear Inclusion Disease

Study type: Observational

Funder types: Other

Identifiers

NCT04055857

7TMRINIID

Details and patient eligibility

About

To discover the microstructure, macrostructure and functional changes with 7T multi-modal magnetic resonance imaging of Neuronal Intranuclear Inclusion Disease, and to explore new biomarkers for evaluating the severity and the progression of Neuronal Intranuclear Inclusion Disease.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients diagnosed with NIID
2. Older than 18 years;
3. Sign the informed consent form.

Exclusion criteria

1. The informed consent is withdrawn by the subject;
2. Contraindications or intolerance to MRI: metallic foreign bodies, instability of vital signs, epilepsy, claustrophobia, etc.

Trial design

30 participants in 2 patient groups

NIID

Description:

NIID patients

HC

Description:

healthy control