Structural and Microbiological Characterization of Arterial Catheter Biofilm in ICU's Patients Using Optical Coherence Tomography (OCT-BIO-KTA)

Centre Hospitalier William Morey - Chalon sur Saône

Status: Enrolling

Conditions: Bacteremia; Tomography, Optical Coherence; Biofilms; Arterial Catheterization, Peripheral

Treatments: Other: OCT-BIO-KTA cohort

Study type: Observational

Funder types: Other

Identifiers

NCT06838598

OCT-BIO-KTA

Details and patient eligibility

About

29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality.

It is now accepted that biofilm as a role on bacterial development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias.

The investigators assume that a better structural and microbiological characterization of arterial catheter biofilm in ICU patients could help preventing bacteremias or have a more specific treatment when it appears.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient or relative informed of the study and having declared their non-objection
• Patient over 18 years old
• Patient hospitalized in ICU with an arterial catheter

Exclusion criteria

• Patient unable to express consent
• Patient whose collection of the arterial catheter is impossible or for whom storage at 4°C is impossible
• Patient with arterial catheter removed outside the usual procedure of the ICU
• Patient admitted in ICU with an arterial catheter already in place

Trial design

60 participants in 1 patient group

OCT-BIO-KTA cohort

Description:

Critically ill patient \> 18 years of age with artherial catheter for \>2 calendar days in ICU

Treatment:

Other: OCT-BIO-KTA cohort