Studies on the Expression and Functions of RLIP76 in Blood Samples of Healthy Human Subjects

University of North Texas Health Science Center

Status: Withdrawn

Conditions: Healthy

Study type: Observational

Funder types: Other

Identifiers

NCT00762801

2008-32

Details and patient eligibility

About

RLIP76 (Ral binding protein1) is a 76 kDa splice variant protein encoded by the human gene (RALBP1, 18p11.22). It is a multifunctional modular protein found ubiquitously from Drosophila to humans, in cells ranging from red blood cells to endothelial cells of the brain. Its expression more predominant in breast, heart, liver and less so in colon and brain parenchyma.

Full description

RLIP76 is shown to be over expressed in a variety of cancer cells. However, no study has yet been done on its expression on normal cells. The studies proposed in this project will study the expression of RLIP76 in blood cells of healthy human subjects in the population of North Texas region.

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy as defined by lack of serious health conditions or diseases

Exclusion criteria

• Children, pregnant women, prisoners, persons with any medical condition that precludes phlebotomy and persons unwilling or unable to provide consent will be excluded.