Study About Predicting Fluid Responsiveness in Children Undergoing Neurosurgery

Seoul National University

Status: Completed

Conditions: Fluid Responsiveness

Treatments: Other: volume expansion

Study type: Interventional

Funder types: Other

Identifiers

NCT01364103

H-1012-118-345

Details and patient eligibility

About

The purpose of this study is to evaluate static and dynamic parameters, echocardiographic parameters, and pleth variability index for predicting fluid responsiveness in children. Children who need volume expansion will receive colloid 10 mL/kg. Blood pressure, heart rate, central venous pressure, systolic pressure variation, pulse pressure variation, delta down, aortic blood flow velocity variation, inferior vena cava diameter variation, and pleth variability index will be measure before and after volume expansion. Patients will be classified as responders to volume loading if stoke volume index increase by at least 15%.

Enrollment: 33 patients

Sex: All

Ages: Under 8 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• neurosurgery under general anesthesia
• < 8 years old

Exclusion criteria

• cardiac disease
• pulmonary, renal and hepatic disease
• infectious disease
• hematologic and muscular disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: Single Blind