Study " COFLORES "

Public Assistance-Hospitals of Marseille (AP-HM)

Status

Completed

Conditions

Myocardial Perfusion

Treatments

Device: sodium-23 MRI

Device: phosphorus-31 Magnetic Resonance Spectroscopy

Device: Magnetic Resonance Imaging (MRI)

Study type

Interventional

Funder types

Other

Identifiers

NCT02848703

2015-45

2016-A00026-45 (Registry Identifier)

Details and patient eligibility

About

Myocardial perfusion is a major parameter characterizing the status of capillary circulation of the myocardium. Its quantification is possible using Magnetic Resonance Imaging (MRI) during the 1st pass of a contrast agent through the capillary system. This technique is radiation-free, but it is difficult to repeat measurements during a single exam. Also, a number of patients suffering from cardiac disease cannot receive contrast agent injections. The investigators have developed a totally non-invasive approach for quantifying myocardial perfusion. It is based on the magnetic labeling of arterial spins. Flowing into the capillaries (Arterial spin labeling, ASL).

Goal : The major goal of this research protocol is to validate a totally non-invasive method of myocardial blood flow quantification using MRI without contrast agent injection

Enrollment

53 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

People having no heart disease or treatment referred to cardiology
People having no cons -indications to MRI
People having no cons -indications to gadolinium ;
People not wearing implantable devices
People not wearing metallic foreign bodies or risk (eg . Business of steel, etc .. )
People having no cardiovascular risk factor
Person subject to the social security scheme
Nobody agreeing to participate in the study and who signed the informed consent

Exclusion criteria