Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty (DA THA pain)

Mayo Clinic

Status: Terminated

Conditions: Degenerative Joint Disease

Treatments: Other: L2 paravertebral block; Other: periarticular injection group

Study type: Interventional

Funder types: Other

Identifiers

NCT02904993

16-001154

Details and patient eligibility

About

To compare two methods of post-operative pain management in patients undergoing total hip arthroplasty. There is a perception that the periarticular injections may not be as effective in controlling post-operative pain.

Both methods are current standard of care. The investigators want to compare the outcomes of each when patients are randomized to one of the methods compared to the other method of post-operative pain control.

Enrollment: 9 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subject scheduled for Direct Anterior unilateral total hip replacement
• Weight ≥ 50 and ≤125 kg
• Intact neurological exam
• Cognitively intact with ability to sign consent

Exclusion criteria

• Renal insufficiency with creatinine > 1.5 mg/dl
• Allergic to any of the following : Ropivacaine, Epinephrine, Ketorolac, Morphine sulfate, NSAIDs, Tylenol, Neurontin, Morphine, Oxycodone or Dilaudid.
• Subject taking regular narcotic medications prior to surgery (20mg/day Morphine equivalents for >7days)
• Subject with prior open hip surgery who received regional anesthesia or periarticular injection for post op pain management.
• Subject with contraindication for spinal anesthesia

Trial design

9 participants in 2 patient groups

L2 paravertebral block

Other group

Description:

regional anesthetic nerve blocks using an L2 paravertebral block with ropivacaine

Treatment:

Other: L2 paravertebral block

periarticular injection group

Active Comparator group

Description:

periarticular local injection into the periarticular soft tissues at the time of hip replacement using a combination of ropivacaine, epinephrine, ketorolac and morphine sulphate (periarticular injection group).

Treatment:

Other: periarticular injection group