Study Comparing the Role of the Laparoscopy Surgical Staging in the Peritoneal Carcinomatosis to Laparotomic Approach (COELIOCHIP)

Civil Hospices of Lyon

Status: Unknown

Conditions: Colorectal Peritoneal Carcinomatosis

Treatments: Other: Non interventional

Study type: Observational

Funder types: Other

Identifiers

NCT02829788

69HCL16_0433

Details and patient eligibility

About

The peritoneum is the second most common site of recurrence in patients with colorectal cancer. Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy improve the prognosis of these patients and incorporates surgical removal of all visible disease followed by chemical destruction of microscopic disease through chemoperfusion. The most validated predictors of outcome are preoperative tumor burden measured in terms of the peritoneal carcinomatosis index (PCI) and completeness of cytoreduction (CC score). Diagnostic laparoscopy prior to resection is widely used in hepatopancreaticobiliary and colorectal cancer and has been shown to be effective in excluding unnecessary laparotomy associated with higher morbidity.

Enrollment: 50 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with Colorectal cancer with a resected minimal synchronous peritoneal carcinomatosis, or ovarian metastases, tumour rupture in the abdominal cavity.
• Patients received six months of systemic chemotherapy (currently the Folfox-4 regimen which could be modified if the standard is modified)

Exclusion criteria

• None

Trial design

50 participants in 1 patient group

Digestive peritoneal carcinomatosis staging

Description:

All patients underwent laparoscopic followed by laparotomic surgical staging.

Treatment:

Other: Non interventional