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Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse

US Department of Veterans Affairs (VA) logo

US Department of Veterans Affairs (VA)

Status

Completed

Conditions

Major Depressive Disorder
Cannabis Abuse
Substance-Related Disorders
Alcohol Abuse

Treatments

Behavioral: Twelve Step Facilitation Therapy
Behavioral: Integrated Cognitive Behavioral Therapy

Study type

Interventional

Funder types

Other U.S. Federal agency

Identifiers

NCT00108407
MHBS-041-99Sa

Details and patient eligibility

About

The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use disorders.

Full description

Depression is the most frequent co-occuring mental health disorder among adults with substance use disorders, and such comorbidity is often associated with poorer treatment outcomes. Although there is an urgent need for effective treatments specific for dual-diagnosis adults, few studies have been conducted to address this need.

Comparison: This study will compare substance use and depression symptoms of individuals in two different psychotherapy groups: Integrated Cognitive Behavioral Therapy and Twelve Step Facilitation Therapy. Symptoms and substance use will be compared during the active treatment phase (24 weeks) and for one year following the end of the active treatment.

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Individuals diagnosed with one or more substance use disorders (alcohol, cannabis, and or stimulant abuse/dependence) and an independent co-occurring depressive disorder (major depression or dysthymia) will be included.

Exclusion criteria

  • Individuals with substance induced mood disorders and individuals experiencing persistent psychotic symptoms.
  • Those with life threatening or unstable medical illness, neurological disorders, or inability to read will be excluded.
  • Individuals currently prescribed steroids, disulfiram, or long acting benzodiazepines will be excluded.

Trial design

0 participants in 2 patient groups

1
Experimental group
Description:
Integrated Cognitive Behavioral Therapy
Treatment:
Behavioral: Integrated Cognitive Behavioral Therapy
2
Experimental group
Description:
Twelve Step Facilitation Therapy
Treatment:
Behavioral: Twelve Step Facilitation Therapy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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