STUDY: Effects of Potatoes in a Weight Loss Program (BBFUSPB)

University of California (UC) Davis

Status: Completed

Conditions: Obesity

Treatments: Behavioral: High Glycemic Index; Behavioral: Low Glycemic Index; Behavioral: Control

Study type: Interventional

Funder types: Other

Identifiers

NCT01186393

200715352

Details and patient eligibility

About

The purpose of this study is to test whether diets that contain potatoes and differ in glycemic index/load will be useful in weight loss, blood sugar control and maintaining current body weight.

Full description

The study will examine the effect of including potatoes as part of a calorie restricted diet designed to induce weight loss and improve glycemic control in overweight subjects.

This is a randomized, treatment-controlled, 3-arm, parallel study. The 3 arms of the study will include dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). Two diets will be energy-restricted (~ 500 kcal deficit /d) for weight loss and the control diet will be prescribed for weight maintenance. The two energy-restricted diets will include further manipulation, such that, one dietary plan will be a high glycemic index (GI) diet and the other a low glycemic index diet.

Enrollment: 90 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men and women
• ≥ 18 years of age who have a body mass index (BMI) of 25 to 35 kg/m2 (inclusive).

Exclusion criteria

• Total cholesterol (TC) not greater than 300 mg/dL,
• Fasting triglyceride not greater than 300 mg/dL ,
• LDL cholesterol (LDL-C) not greater than 180 mg/dL,
• Smokers
• Female subjects who are pregnant or lactating
• Subjects taking any medications that would interfere with outcomes of the study
• Subjects with unusual dietary habits (eg., pica)
• Subjects who are actively losing weight or trying to lose weight
• Subjects who are addicted to drugs or alcohol or who are < 1 y in recovery program
• Subjects who present with significant psychiatric or neurological disturbances
• Subjects with known allergy or intolerance to potato products
• Subjects with documented atherosclerotic disease, inflammatory disease, diabetes mellitus, uncontrolled hypertension ( 140/90 mm Hg), chronic lung, renal or liver disease

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

90 participants in 3 patient groups

Control

Experimental group

Description:

Arm includes dietary manipulation in the free-living setting to include potatoes/potato products frequently in the diet (5-7 days / week). Control diet will be prescribed for weight maintenance.

Treatment:

Behavioral: Control

Low Glycemic Index

Experimental group

Description:

Diets will be energy-restricted (\~ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on Low Glycemic Index foods.

Treatment:

Behavioral: Low Glycemic Index

High Glycemic Index

Experimental group

Description:

Diets will be energy-restricted (\~ 500 kcal deficit /d) for weight loss, will include consumption of 5-7 potatoes/week, and will focus on High Glycemic Index foods.

Treatment:

Behavioral: High Glycemic Index