Study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia (modafinil)

Ain Shams University

Status: Completed

Conditions: Bariatric Surgery; Obese Adolescents

Treatments: Drug: Modafinil

Study type: Interventional

Funder types: Other

Identifiers

NCT07128719

FAMSU MS 412/2023

Details and patient eligibility

About

study Effects of Preoperative Modafinil on Recovery Profile of Morbidly Obese Patients Scheduled for Bariatric Surgery if it Can Enhance Recovery From Anesthesia and provide improvement in recovery

Full description

The study was conducted to 20 patients scheduled for bariatric surgeries. The study group (Modafinil group) received oral 200 mg modafinil 8 hours before surgery and then another 200 mg 2 hours before surgery. The other group (Placebo group) were given placebo through the same regimen as Modafinil. Immediate recovery time, cognitive recovery, emotional (general) status, discharge from PACU according to modified Aldrete score were assessed.

Enrollment: 20 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients aged from 18 to 60 years.
2. Patients ASA II or III undergoing elective bariatric surgery.
3. BMI 30-50 kg/m2.

Exclusion criteria

1. Patient's refusal.
2. Age below 18 or above 60y.
3. History of cardiac disease.
4. History or known allergy to Modafinil.
5. Underlying liver or renal failure.
6. Chronic neurological or psychiatric condition.
7. Hemodynamically unstable patients.
8. History of drug dependance.
9. Habitual coffee consumption exceeding 2 cups per day.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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20 participants in 2 patient groups, including a placebo group

10 patients received modafinil preoperatively

Active Comparator group

Description:

assessing enhancement of recovery from anesthesia

Treatment:

Drug: Modafinil

10 patients didnot receive modafinil preoperatively

Placebo Comparator group

Treatment:

Drug: Modafinil