Study: Effects of Strawberries on Blood Pressure (CSCBP)

University of California (UC) Davis

Status: Completed

Conditions: Pre-hypertension

Treatments: Other: Strawberry Beverage; Other: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01190319

200715153

Details and patient eligibility

About

The specific aim of the study is to determine whether a freeze dried powder provided by the California Strawberries Commission, can reduce blood pressure in patients with pre-hypertension. The powder is prepared by the California Strawberry Commission (CSC).

Full description

Primarily, we would like to find out whether freeze dried strawberry powder lowers blood pressure. In addition we would like to know if the strawberry alters the subject's blood cholesterol and the ability of the subject's blood vessels to relax.

Enrollment: 50 patients

Sex: All

Ages: 25 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pre-hypertensive men and women (JNC 7 [The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure] criteria) between the ages of 25 and 65 years who have no clinical evidence/history of cardiovascular, respiratory, renal, gastrointestinal or hepatic disease.

Exclusion criteria

• Subjects who:

  1. are taking over the counter anti-oxidant supplements,
  2. are taking prescription medications that may interfere with study procedures or endpoints,
  3. have unusual dietary habits (eg., pica),
  4. are actively losing weight or trying to lose weight,
  5. are addicted to drugs or alcohol,
  6. present with significant psychiatric or neurological disturbances,
  7. have known allergies to strawberry, will be excluded from participating in this study.
  8. Patients known to have glaucoma
  9. Pregnant and/or lactating females

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups, including a placebo group

Placebo Beverage

Placebo Comparator group

Description:

The placebo beverage is matched in energy, macronutrient composition and sensory properties to the active beverage, but is devoid of strawberry polyphenols.

Treatment:

Other: Placebo

Strawberry Beverage

Experimental group

Description:

The strawberry beverage is matched in energy, macronutrient composition and sensory properties to the placebo beverage, but contains strawberry polyphenols.

Treatment:

Other: Strawberry Beverage