Study Evaluating MOA-728 Administered in Healthy Men

Bausch Health

Status and phase: Withdrawn; Phase 1

Conditions: Healthy

Treatments: Drug: MOA-728

Study type: Interventional

Funder types: Industry

Identifiers

NCT00427258

3200A3-1106

Details and patient eligibility

About

Absorption, distribution, metabolism, and excretion (ADME) study with 14C in healthy young men.

Sex: Male

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Men aged 18 to 50 years inclusive at screening.
• Body mass index (BMI) in the range of 18.0 to 30.0 kg/m2 and body weight ≥50 kg. BMI is calculated by taking the subject's weight, in kilograms, divided by the square of the subject's height, in meters, at screening: BMI = weight (kg)/[height (m)]2
• Healthy as determined by the investigator on the basis of screening evaluations.
• Nonsmoker or smoker of fewer than 10 cigarettes per day as determined by history. Must be able to abstain from smoking during the inpatient stay.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)