Study Evaluating Oral MOA-728 in Subjects on Methadone Therapy

Bausch Health

Status and phase: Withdrawn; Phase 1

Conditions: Methadone-maintenance Subjects

Treatments: Drug: MOA-728

Study type: Interventional

Funder types: Industry

Identifiers

NCT00505583

3200A3-1110

Details and patient eligibility

About

To evaluate the effects of single oral doses of MOA-728 compared to a positive control in subjects on methadone therapy.

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion:

1. Healthy men or women, aged 18 to 65 years.
2. History of methadone treatment for at least 1 month, at a dose >=30 and <=140 mg/day.

Exclusion:

1. History or active presence of clinically important medical disease.
2. Allergy to opioids.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind