Study Evaluating Pantoprazole in Peptic Ulcer Hemorrhage

Wyeth

Status and phase: Completed; Phase 3

Conditions: Peptic Ulcer Hemorrhage

Treatments: Drug: Pantoprazole

Study type: Interventional

Funder types: Industry

Identifiers

NCT00040495

3001K2-315

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy and safety of intravenous pantoprazole in the prevention of rebleeding in patients with bleeding peptic ulcer disease after successful endoscopic hemostatic therapy.

Enrollment: 149 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients must be men or non-pregnant women at least 18 years of age
• Patients who present with a gastric or duodenal ulcer

Exclusion criteria

• Patients with ulcer appearance of clean base (non-oozing, non-spurting) or flat pigmented spot; adherent clots not removed by irrigation
• Patients presenting with active bleeding and/or NBVV at 2 or more separate sites
• Patients with any severe concomitant diseases, eg, end stage liver or renal disease, or unstable cardiovascular, pulmonary, renal, hepatic, or gastrointestinal diseases