Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis (PRURI-MUSIC)

Regional University Hospital Center (CHRU)

Status: Completed

Conditions: Pruritus

Treatments: Other: evaluation of the intensity of pruritus

Study type: Interventional

Funder types: Other

Identifiers

NCT03701971

29BRC18.0112

Details and patient eligibility

About

Many clinical studies have shown the benefit of music therapy in various pathologies, including pain, and it is now established that the latter has a complementary therapeutic interest. Its most frequently identified indications are the fight against acute or chronic pains, the reduction of anxiety, depression and stress, as well as memory disorders such as Alzheimer's disease.

The main modes of action of music therapy involve sensory, cognitive, psychological and behavioral processes that are also found in pruritus.

Pruritus is defined as "an uncomfortable sensation causing the need to scratch. It has similarities with pain but also differences: relief by heat / cold, scratching / withdrawal behavior, localization on the skin, semi-mucous / ubiquitous ... etc.

The pathophysiology also has similarities, pruritus is born at the dermal-epidermal junction at the level of specific cutaneous receptors then follows the classical pathways through a 1st neuron, then the dorsal horn of the spinal cord and a second neuron. At the cerebral level, there is no single center of pruritus but several motor and sensory areas involved.

The similarities suggest that music therapy may have an interest in the management of chronic pruritus, especially since classical treatments (antihistamines, topical corticosteroids) have only partial efficacy in some dermatoses

Enrollment: 50 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• At least 18 years of age
• Patient with pruritic dermatosis whatever the etiology (psoriasis, atopic dermatitis, toxiderma, cutaneous lymphoma, chronic urticaria ...)
• Hospitalized in continuous hospitalization in the Dermatology Department
• Age of dermatosis ≥ 1 month
• Pruritus score ≥ 3/10 by numerical evaluation
• Patient having signed a consent form

Exclusion criteria

• Patient under the age of 18
• Major impairment of hearing function
• Presence of major cognitive disorders
• Refusal to participate
• Pregnant or lactating women
• Institutionalized or emergency patients
• Patient under legal protection regime
• Patient not affiliated to the social security system

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Music Therapy

Experimental group

Description:

* a medical examination * Before and after music therapy, patients will have to answer questionnaires : Before : Questionnaire 5D itch scale Itchy Quality of Life Pruritus assessment on the digital scale Questionnaire State-Trait Anxiety Inventory (STAI Y-A) After : Pruritus assessment on the digital scale Questionnaire State-Trait Anxiety Inventory (STAI Y-A) PGIC • Patients will then benefit from a balneotherapy session the next morning. Patients will have to answer questionnaires before and after balneotherapy : Before : Pruritus assessment on the digital scale Questionnaire State-Trait Anxiety Inventory (STAI Y-A) After : Pruritus assessment on the digital scale Questionnaire State-Trait Anxiety Inventory (STAI Y-A) PGIC

Treatment:

Other: evaluation of the intensity of pruritus

Emollient cream

Active Comparator group

Description:

* a medical examination * Before and after music therapy, patients will have to answer questionnaires : Before : * Questionnaire 5D itch scale * Itchy Quality of Life * Pruritus assessment on the digital scale * Questionnaire State-Trait Anxiety Inventory (STAI Y-A) After : * Pruritus assessment on the digital scale * Questionnaire State-Trait Anxiety Inventory (STAI Y-A) * PGIC * Patients will then benefit from a balneotherapy session the next morning. Patients will have to answer questionnaires before and after balneotherapy : Before : * Pruritus assessment on the digital scale * Questionnaire State-Trait Anxiety Inventory (STAI Y-A) After : * Pruritus assessment on the digital scale * Questionnaire State-Trait Anxiety Inventory (STAI Y-A) * PGIC

Treatment:

Other: evaluation of the intensity of pruritus